The SLC22A12 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SLC22A12, and URAT1. This antibody recognizes Human, Mouse, and Rat antigen. The SLC22A12 Polyclonal Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants